Connect with us

Medical doctors and Surgeons

The sentinel lymph node for early diagnosis

Published

on

When it comes breast cancer, the sentinel lymph node is the first to be affected by metastases. It is indeed an important parameter to consider for studying and determining the stage of the disease.

«From the breast, via the lymphatic pathways metastases reach the axillary cavity. This area is, in fact, full of lymph nodes, which are the first to be affected by metastatic cells in case of breast cancer – says Diego Ribuffo, professor of plastic surgery at the University of La Sapienza in Rome and a member of the Breast Unit at Umberto I -. If the sentinel lymph node is negative, which means free of metastases then all the others will be as well».

Depending on the number of lymph nodes involved and the amount of metastasis found in this lymph node, it is possible to get an overall picture of the disease and determine subsequent therapies.

How to identify the sentinel lymph node

The procedure to detect and to analyse the sentinel lymph node is very specific and is performed in Breast Units. It is a procedure that avoids lymph node dissection and thus the removal of all lymph nodes in the axillary region, which often causes lymphedema after a mastectomy.

Diego Ribuffo, professor of Plastic Surgery, director of the Specialisation School in Plastic, Reconstructive, and Aesthetic Surgery, coordinator of the PhD program in Innovative Technologies in Diseases of the Skeletal, Cutaneous, and Oro-Cranio-Facial District, director of the second-level Master’s degree in Orthoplasty at Sapienza University of Rome

«To identify the sentinel lymph node, the tissues near the tumor must be marked with a radiopharmaceutical. This is injected into the affected area, and with a probe that detects very low-level radiation, two or three nodes are identified – explains Ribuffo -. To analyse them, a histological examination with special markers is necessary because what we are looking for are not the so-called macro metastases, but rather single cells».

Looking to the future of breast cancer treatment, Professor Ribuffo, who primarily focuses on breast reconstruction, has an encouraging outlook on care and treatment procedures. He talks about prophylactic mastectomy, which is a preventive surgery. This procedure involves removing the entire gland wile preserving the outer envelope, including the skin, dermis, and nipple.

«The scenario for the next 20 years will likely involve fewer procedures by breast surgeons and more interventions by plastic surgeons to treat necrosis caused by chemotherapy or radiotherapy. Axillary dissection is now very rare, and very few patients will undergo these types of surgeries – Ribuffo continues -. Thanks to advances in genetics and genomics, we will be able to identify patients with particular mutations who are thus candidates for customised chemotherapy or radiotherapy».

The role of Breast Units

When it comes to breast cancer prevention, ultrasound and mammography are the main tests performed for early diagnosis.

«Despite screening being free, also proposed by regions through a letter sent home, and despite constantly being positively addressed in the media, only just over half of Italian women in the screening age group undergo the test. In addition to regular exams, self-checks through self-examination and inspection that can be performed daily by the patient herself are essential», explains the professor.

Ribuffo also emphasises the importance of relying on Breast Units to receive personalised and timely treatment. «The benefits are numerous. It has been shown that being treated in these centres increases the chances of survival for patients. Within Breast Units, there is a strong collaboration among specialists in various field dedicated to a single pathology. They study, discuss cases and sinergistically find a shared therapy», Ribuffo concludes.


Discover more from Revèe News

Subscribe to get the latest posts to your email.

Psychologists3 days ago

Gender dysphoria, how to recognise it in children

Medical doctors and Surgeons1 week ago

Gender dysphoria: the importance of surgery

Medical doctors and Surgeons2 weeks ago

Regenerating tissue through stem cells

attualità in ricostruzione mammaria autologa, protesica ed ibrida
Events and conventions4 weeks ago

Trends in autologous, prosthetic, and hybrid breast surgery

Medical doctors and Surgeons4 weeks ago

What does conservative surgery mean?

Events and conventions4 weeks ago

GTVER Congress in Bologna on May 24-25

Medical doctors and Surgeons1 month ago

The sentinel lymph node for early diagnosis

Health care professionals1 month ago

“Nurturing health”: celebrating the role of nurses

Events and conventions1 month ago

Breast surgery: hot topics and behavioural guidelines 

Medical doctors and Surgeons1 month ago

Anomalies beyond appearances: Poland Syndrome

Events and conventions2 months ago

“Tutto il grasso minuto per minuto”: a congress on fat

Associations2 months ago

“I Girasoli” next to oncological patients

V.I.T.A
Associations2 months ago

V.I.T.A.: a quarter century of fighting against breast cancer

Events and conventions2 months ago

Cosmofarma Exhibition: Revée participates in the 27th edition

filler
Medical doctors and Surgeons2 months ago

Fillers: innovative trends and practices

Events and conventions2 months ago

11th National Congress of AICPE

cicatrici
Revée pills2 months ago

How to treat scars?

Associations3 months ago

“Bici in Rosa”: promoting prevention and healthy lifestyle

Events and conventions3 months ago

The holistic approach to diastasis

Medical doctors and Surgeons3 months ago

Innovation and research in the fight against breast cancer

Associations3 months ago

Diastasi Italia: network of specialised professionals

Events and conventions3 months ago

The holistic approach to diastasis

Associations2 months ago

“I Girasoli” next to oncological patients

Associations3 months ago

“Bici in Rosa”: promoting prevention and healthy lifestyle

mammella
Events and conventions3 months ago

Breast Aesthetic Surgery: First AICPE Training Course of 2024

cicatrici
Revée pills2 months ago

How to treat scars?

filler
Medical doctors and Surgeons2 months ago

Fillers: innovative trends and practices

Events and conventions2 months ago

11th National Congress of AICPE

V.I.T.A
Associations2 months ago

V.I.T.A.: a quarter century of fighting against breast cancer

Medical doctors and Surgeons1 month ago

Anomalies beyond appearances: Poland Syndrome

Health care professionals1 month ago

“Nurturing health”: celebrating the role of nurses

Medical doctors and Surgeons1 month ago

The sentinel lymph node for early diagnosis

Medical doctors and Surgeons4 weeks ago

What does conservative surgery mean?

Events and conventions2 months ago

Cosmofarma Exhibition: Revée participates in the 27th edition

Events and conventions2 months ago

“Tutto il grasso minuto per minuto”: a congress on fat

Events and conventions1 month ago

Breast surgery: hot topics and behavioural guidelines 

attualità in ricostruzione mammaria autologa, protesica ed ibrida
Events and conventions4 weeks ago

Trends in autologous, prosthetic, and hybrid breast surgery

Medical doctors and Surgeons2 weeks ago

Regenerating tissue through stem cells

Copyright © 2022 Revée News. Periodico di informazione sul mondo Chirurgia e del Benessere | Registrazione Tribunale di Torino n. 21 il 17/10/2023 |
Direttore responsabile Debora Pasero | Edito da REVEE SRL - corso Quintino Sella, 131 - Torino C.F. 10818580010

Discover more from Revèe News

Subscribe now to keep reading and get access to the full archive.

Continue reading